Safety and immunogenicity of three dose levels of an investigational, highly purified Vero cell rabies vaccine: A randomized, controlled, observer-blinded, Phase II study with a simulated post-exposure regimen in healthy adults

• Main Authors: Sylvie Pichon (Author), Francoise Guinet-Morlot (Author), Jamshid Saleh (Author), Brandon Essink (Author), Andrea-Clemencia (Author), Annick Moureau (Author), Celine Petit (Author), Ada-Maria Minutello (Author)
• Format: Book
• Published: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

ABSTRACTA serum-free, highly purified rabies vaccine produced in Vero cells is under development. The initial formulation, PVRV-NG, was evaluated in five Phase II studies and subsequently reformulated (PVRV-NG2). This multicenter, observer-blinded Phase II study investigated the safety and immune re...