TREM1: Activation, signaling, cancer and therapy

• Ngā kaituhi matua: Chenyang Li (Author), Chujun Cai (Author), Dafeng Xu (Author), Xiaoping Chen (Author), Jia Song (Author)
• Hōputu: Pukapuka
• I whakaputaina: Elsevier, 2024-06-01T00:00:00Z.
• Ngā marau: article
• Urunga tuihono: Connect to this object online.

Triggering receptor expressed on myeloid cells 1 (TREM1) is a cell surface receptor expressed on neutrophils, monocytes and some tissue macrophages, where it functions as an immunoregulator that controls myeloid cell responses. The activation of TREM1 is suggested to be an upregulation-based, ligand...