S-Allylmercaptocysteine improves alcoholic liver disease partly through a direct modulation of insulin receptor signaling

• Main Authors: Pingping Luo (Author), Ming Zheng (Author), Rui Zhang (Author), Hong Zhang (Author), Yingxia Liu (Author), Wei Li (Author), Xiaoming Sun (Author), Qian Yu (Author), George L. Tipoe (Author), Jia Xiao (Author)
• Format: Book
• Published: Elsevier, 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Alcoholic liver disease (ALD) causes insulin resistance, lipid metabolism dysfunction, and inflammation. We investigated the protective effects and direct regulating target of S-allylmercaptocysteine (SAMC) from aged garlic on liver cell injury. A chronic ethanol-fed ALD in vivo model (the NIAAA mod...