Macrophages enhance Vegfa-driven angiogenesis in an embryonic zebrafish tumour xenograft model

• Main Authors: Denver D. Britto (Author), Barbara Wyroba (Author), Wenxuan Chen (Author), Rhoswen A. Lockwood (Author), Khanh B. Tran (Author), Peter R. Shepherd (Author), Christopher J. Hall (Author), Kathryn E. Crosier (Author), Philip S. Crosier (Author), Jonathan W. Astin (Author)
• Format: Book
• Published: The Company of Biologists, 2018-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Tumour angiogenesis has long been a focus of anti-cancer therapy; however, anti-angiogenic cancer treatment strategies have had limited clinical success. Tumour-associated myeloid cells are believed to play a role in the resistance of cancer towards anti-angiogenesis therapy, but the mechanisms by w...