Influence of Stabilizer on the Development of Luteolin Nanosuspension for Cutaneous Delivery: An In Vitro and In Vivo Evaluation

• Main Authors: Mohammed Elmowafy (Author), Khaled Shalaby (Author), Mohammad M. Al-Sanea (Author), Omnia M. Hendawy (Author), Ayman Salama (Author), Mohamed F. Ibrahim (Author), Mohammed M. Ghoneim (Author)
• Format: Book
• Published: MDPI AG, 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Luteolin is a natural drug used as an antioxidant and anti-inflammatory, but unfortunately, it possesses low water solubility, which hinders its delivery via the skin. The main objective of this study was to prepare a luteolin-loaded nanosuspension by the antisolvent precipitation/sonication techniq...