Potential synergic mechanism of Wutou-Gancao herb-pair by inhibiting efflux transporter P-glycoprotein

• मुख्य लेखकों: Yufei He (लेखक), Zihong Wei (लेखक), Ying Xie (लेखक), Xiulin Yi (लेखक), Yong Zeng (लेखक), Yazhuo Li (लेखक), Changxiao Liu (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2020-04-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Wutou-Gancao herb-pair is extensively used to attenuate the toxicity and enhance the efficacy of aconite. In this study, potential synergic mechanism of the herb pair was investigated by utilizing multiple approaches. In silico and in vitro Caco-2 cell models were applied to study the potential bind...