Physiologically Based Pharmacokinetic (PBPK) Modeling for Predicting Brain Levels of Drug in Rat

One of the main obstacles in neurological disease treatment is the presence of the blood-brain barrier. New predictive high-throughput screening tools are essential to avoid costly failures in the advanced phases of development and to contribute to the 3 Rs policy. The objective of this work was to...

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Bibliographic Details
Main Authors: Bárbara Sánchez-Dengra (Author), Isabel Gonzalez-Alvarez (Author), Marival Bermejo (Author), Marta Gonzalez-Alvarez (Author)
Format: Book
Published: MDPI AG, 2021-09-01T00:00:00Z.
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3rd Floor Main Library

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