Prophylactic administration of tranexamic acid combined with thromboelastography-guided hemostatic algorithm reduces allogeneic transfusion requirements during pediatric resective epilepsy surgery: A randomized controlled trial

• Main Authors: Ting Zhang (Author), Hua Feng (Author), Wei Xiao (Author), Jingsheng Li (Author), Qinghai Liu (Author), Xuexin Feng (Author), Dezhou Qi (Author), Xiaotong Fan (Author), Yongzhi Shan (Author), Tao Yu (Author), Guoguang Zhao (Author), Tianlong Wang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Intraoperative bleeding and allogeneic transfusion remain common problems in pediatric resective epilepsy surgery. Tranexamic acid (TXA) is a widely recommended antifibrinolytic drug that reduces blood loss and transfusion requirements for bleeding patients. Thromboelastography (TEG)-gui...