Phase I Study in Healthy Women of a Novel Antimycotic Vaginal Ovule Combining Econazole and Benzydamine

• Main Authors: A. F. D. Di Stefano (Author), M. M. Radicioni (Author), A. Vaccani (Author), G. Caccia (Author), F. Focanti (Author), E. Salvatori (Author), F. Pelacchi (Author), R. Picollo (Author), M. T. Rosignoli (Author), S. Olivieri (Author), G. Bovi (Author), A. Comandini (Author)
• Format: Book
• Published: Hindawi Limited, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose. A novel fixed-dose combination of 150 mg of econazole with 6 mg of benzydamine formulated in vaginal ovules was investigated in a randomised, double-blind, four-parallel group, tolerability, and pharmacokinetic Phase I study in healthy women. Methods. The fixed-dose combination was compared...