Pharmacokinetics of five phthalides in volatile oil of Ligusticum sinense Oliv.cv. Chaxiong, and comparison study on physicochemistry and pharmacokinetics after being formulated into solid dispersion and inclusion compound

• Main Authors: Peng-yi Hu (Author), Ying-huai Zhong (Author), Jian-fang Feng (Author), Dong-xun Li (Author), Ping Deng (Author), Wen-liu Zhang (Author), Zhi-qiang Lei (Author), Xue-mei Liu (Author), Guo-song Zhang (Author)
• Format: Book
• Published: BMC, 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Backgrounds The dried rhizome of Ligusticum sinense Oliv.cv. Chaxiong has been used to treat cardiovascular and cerebrovascular diseases, atherosclerosis, anemia and stroke. A high purity extract from chaxiong (VOC, brownish yellow oil) was extracted and separated. Its main components were...