Extracellular Vesicles Derived from Selenium-Deficient MAC-T Cells Aggravated Inflammation and Apoptosis by Triggering the Endoplasmic Reticulum (ER) Stress/PI3K-AKT-mTOR Pathway in Bovine Mammary Epithelial Cells

• Main Authors: Yu Chen (Author), Xiangqian Zhang (Author), Jing Yang (Author), Wen Feng (Author), Ganzhen Deng (Author), Shiwen Xu (Author), Mengyao Guo (Author)
• Format: Bog
• Udgivet: MDPI AG, 2023-12-01T00:00:00Z.
• Fag: article
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Selenium (Se) deficiency disrupts intracellular REDOX homeostasis and severely deteriorates immune and anti-inflammatory function in high-yielding periparturient dairy cattle. To investigate the damage of extracellular vesicles derived from Se-deficient MAC-T cells (SeD-EV) on normal mammary epithel...