5-aza-2',2'-Difluoro Deoxycytidine (NUC013): A Novel Nucleoside DNA Methyl Transferase Inhibitor and Ribonucleotide Reductase Inhibitor for the Treatment of Cancer

Tumor suppressor genes can be silenced genetically as well as epigenetically. One approach to reversing epigenetic suppression of tumor suppressor genes is to inhibit DNA methyl transferase. 5-aza-2',2'-difluorodeoxycytidine (NUC013) is a novel DNA methyl transferase and ribonucleotide red...

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Bibliographic Details
Main Authors: Richard Daifuku (Author), Zhenbo Hu (Author), Yogen Saunthararajah (Author)
Format: Book
Published: MDPI AG, 2017-07-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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