Antibody blockade of activin type II receptors preserves skeletal muscle mass and enhances fat loss during GLP-1 receptor agonism

• Үндсэн зохиолчид: Elizabeth Nunn (Зохиогч), Natasha Jaiswal (Зохиогч), Matthew Gavin (Зохиогч), Kahealani Uehara (Зохиогч), Megan Stefkovich (Зохиогч), Karima Drareni (Зохиогч), Ryan Calhoun (Зохиогч), Michelle Lee (Зохиогч), Corey D. Holman (Зохиогч), Joseph A. Baur (Зохиогч), Patrick Seale (Зохиогч), Paul M. Titchenell (Зохиогч)
• Формат: Ном
• Хэвлэсэн: Elsevier, 2024-02-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Objective: Glucagon-like peptide 1 (GLP-1) receptor agonists reduce food intake, producing remarkable weight loss in overweight and obese individuals. While much of this weight loss is fat mass, there is also a loss of lean mass, similar to other approaches that induce calorie deficit. Targeting sig...