Association between vitamin D plasma concentrations and VDR gene variants and the risk of premature birth

• Main Authors: Letícia Veríssimo Dutra (Author), Fernando Alves Affonso-Kaufman (Author), Fernanda Ramires Cafeo (Author), Milene Saori Kassai (Author), Caio Parente Barbosa (Author), Francisco Winter Santos Figueiredo (Author), Fabíola Isabel Suano-Souza (Author), Bianca Bianco (Author)
• Format: Book
• Published: BMC, 2019-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Premature birth is the main cause of mortality in children under 1 year, and vitamin D deficiency during gestation is associated with prematurity. The effects of vitamin D are mediated by its receptor, which is encoded by the VDR gene. VDR variants-such as single nucleotide varia...