Generation of iPSCs by Nonintegrative RNA-Based Reprogramming Techniques: Benefits of Self-Replicating RNA versus Synthetic mRNA

• Main Authors: Heidrun Steinle (Author), Marbod Weber (Author), Andreas Behring (Author), Ulrike Mau-Holzmann (Author), Christian Schlensak (Author), Hans Peter Wendel (Author), Meltem Avci-Adali (Author)
• Format: Book
• Published: Hindawi Limited, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The reprogramming of somatic cells into induced pluripotent stem cells (iPSCs) is gaining in importance in the fields of regenerative medicine, tissue engineering, and disease modeling. Patient-specific iPSCs have as an unlimited cell source a tremendous potential for generating various types of aut...