Protocol for the diagnostic performance of C reactive protein, procalcitonin and interleukin-6 for serious bacterial infections among children ≤36 months old presenting with fever without source: a systematic review and meta-analysis

• Main Authors: Shu-Ling Chong (Author), Rehena Sultana (Author), Sarah Hui Wen Yao (Author), Sharon Si Min Goh (Author), Natalia Sutiman (Author)
• Format: Book
• Published: BMJ Publishing Group, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction The management of fever without source in children ≤36 months old remains a diagnostic challenge as the underlying aetiologies can vary from self-limiting viral infections to serious bacterial infections (SBIs). Biomarkers such as C reactive protein (CRP), procalcitonin (PCT) and interl...