Curcumin derivative, 2,6-bis(2-fluorobenzylidene)cyclohexanone (MS65) inhibits interleukin-6 production through suppression of NF-κB and MAPK pathways in histamine-induced human keratinocytes cell (HaCaT)

• Prif Awduron: Nurul Atika Razali (Awdur), Nur Amiza Nazarudin (Awdur), Kok Song Lai (Awdur), Faridah Abas (Awdur), Syahida Ahmad (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: BMC, 2018-07-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

Abstract Background Histamine is a well-known mediator involved in skin allergic responses through up-regulation of pro-inflammatory cytokines. Antihistamines remain the mainstay of allergy treatment, but they were found limited in efficacy and associated with several common side effects. Therefore,...