Synthetic arylquinuclidine derivatives exhibit antifungal activity against <it>Candida albicans</it>, <it>Candida tropicalis </it>and <it>Candida parapsilopsis</it>

• Main Authors: Gilbert Ian (Author), de Souza Wanderley (Author), Urbina Julio A (Author), Cammerer Simon (Author), Fernandes Rodrigues Juliany (Author), Ishida Kelly (Author), Rozental Sonia (Author)
• Format: Book
• Published: BMC, 2011-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Sterol biosynthesis is an essential pathway for fungal survival, and is the biochemical target of many antifungal agents. The antifungal drugs most widely used to treated fungal infections are compounds that inhibit cytochrome P450-d...