The Effects of Lyophilization on the Physico-Chemical Stability of Sirolimus Liposomes

• Main Authors: Parvin Zakeri-Milani (Author), Hadi Valizadeh (Author), Saeed Ghanbarzadeh (Author)
• Formato: Livro
• Publicado em: Tabriz University of Medical Sciences, 2013-02-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Purpose: The major limitation in the widespread use of liposome drug delivery system is its instability. Lyophilization is a promising approach to ensure the long-term stability of liposomes. The aim of this study was to prepare sirolimus-loaded liposomes, study their stability and investigate the e...