Berberine Improves Glucose and Lipid Metabolism in HepG2 Cells Through AMPKα1 Activation

AimThis study is designed to investigate whether or not AMP-activated protein kinase α1 (AMPKα1) is required for natural product berberine (BBR) to improve glucose and lipid metabolism in HepG2 cells.MethodsAMPKα1 knocked-out (KO, AMPKα1-/-) cells were obtained by co-transfection of the CRISPR/Cas9...

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Main Authors: Gang Ren (Author), Jiang-Hong Guo (Author), Yu-Zhen Qian (Author), Wei-Jia Kong (Author), Jian-Dong Jiang (Author)
Format: Book
Published: Frontiers Media S.A., 2020-05-01T00:00:00Z.
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