The role of GluN2A and GluN2B NMDA receptor subunits in AgRP and POMC neurons on body weight and glucose homeostasis

• Main Authors: Aykut Üner (Author), Gabriel H.M. Gonçalves (Author), Wenjing Li (Author), Matheus Porceban (Author), Nicole Caron (Author), Milena Schönke (Author), Eric Delpire (Author), Kenji Sakimura (Author), Christian Bjørbæk (Author)
• Format: Book
• Published: Elsevier, 2015-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Hypothalamic agouti-related peptide (AgRP) and pro-opiomelanocortin (POMC) expressing neurons play critical roles in control of energy balance. Glutamatergic input via n-methyl-d-aspartate receptors (NMDARs) is pivotal for regulation of neuronal activity and is required in AgRP neurons fo...