A combination of metformin and epigallocatechin gallate potentiates glioma chemotherapy in vivo

• Main Authors: Shreyas S. Kuduvalli (Author), Precilla S. Daisy (Author), Anandraj Vaithy (Author), Mugilarasi Purushothaman (Author), Arumugam Ramachandran Muralidharan (Author), Kumar B. Agiesh (Author), Markus Mezger (Author), Justin S. Antony (Author), Madhu Subramani (Author), Biswajit Dubashi (Author), Indrani Biswas (Author), K. P. Guruprasad (Author), T. S. Anitha (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Glioma is the most devastating high-grade tumor of the central nervous system, with dismal prognosis. Existing treatment modality does not provide substantial benefit to patients and demands novel strategies. One of the first-line treatments for glioma, temozolomide, provides marginal benefit to gli...