Design, Synthesis, and Biological Evaluation of PKD Inhibitors

• Main Authors: Marie-Céline Frantz (Author), Karla Bravo-Altamirano (Author), Courtney R. LaValle (Author), Manuj Tandon (Author), Stephanie Leimgruber (Author), Elizabeth R. Sharlow (Author), John S. Lazo (Author), Q. Jane Wang (Author), Peter Wipf (Author), Kara M. George (Author)
• Format: Book
• Published: MDPI AG, 2011-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Protein kinase D (PKD) belongs to a family of serine/threonine kinases that play an important role in basic cellular processes and are implicated in the pathogenesis of several diseases. Progress in our understanding of the biological functions of PKD has been limited due to the lack of a PKD-specif...