Protective Effect of Sauchinone on Methamphetamine-Induced Neurotoxicity in Mice

• Main Authors: Eun Young Jang (Author), Kyung Ah Park (Author), Jong Rock Lee (Author), Chae Ha Yang (Author), Meeyul Hwang (Author)
• Format: Book
• Published: Elsevier, 2012-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Sauchinone is a lignan isolated from Saururus chinensis known to suppress nitric oxide (NO) activity. Previous studies demonstrate that NO plays a key role in methamphetamine-induced neurotoxicity. Thus, we hypothesized that sauchinone could have a suppressive effect on the neurotoxicity induced by...