Characterization and Pharmacokinetic Assessment of a New Berberine Formulation with Enhanced Absorption In Vitro and in Human Volunteers

• Main Authors: Julia Solnier (Author), Yiming Zhang (Author), Yun Chai Kuo (Author), Min Du (Author), Kyle Roh (Author), Roland Gahler (Author), Simon Wood (Author), Chuck Chang (Author)
• Format: Book
• Published: MDPI AG, 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Berberine is a plant-origin quaternary isoquinoline alkaloid with a vast array of biological activities, including antioxidant and blood-glucose- and blood-lipid-lowering effects. However, its therapeutic potential is largely limited by its poor oral bioavailability. The aim of this study was to inv...