miR-429-3p mediates memory decline by targeting MKP-1 to reduce surface GluA1-containing AMPA receptors in a mouse model of Alzheimer's disease

• Egile Nagusiak: Man Luo (Egilea), Yayan Pang (Egilea), Junjie Li (Egilea), Lilin Yi (Egilea), Bin Wu (Egilea), Qiuyun Tian (Egilea), Yan He (Egilea), Maoju Wang (Egilea), Lei Xia (Egilea), Guiqiong He (Egilea), Weihong Song (Egilea), Yehong Du (Egilea), Zhifang Dong (Egilea)
• Formatua: Liburua
• Argitaratua: Elsevier, 2024-02-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Alzheimer's disease (AD) is a leading cause of dementia in the elderly. Mitogen-activated protein kinase phosphatase 1 (MKP-1) plays a neuroprotective role in AD. However, the molecular mechanisms underlying the effects of MKP-1 on AD have not been extensively studied. MicroRNAs (miRNAs) regula...