Evaluating and Improving Neonatal Gentamicin Pharmacokinetic Models Using Aggregated Routine Clinical Care Data

Model-informed precision dosing (MIPD) can aid dose decision-making for drugs such as gentamicin that have high inter-individual variability, a narrow therapeutic window, and a high risk of exposure-related adverse events. However, MIPD in neonates is challenging due to their dynamic development and...

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Main Authors: Dominic M. H. Tong (Author), Jasmine H. Hughes (Author), Ron J. Keizer (Author)
Format: Book
Published: MDPI AG, 2022-09-01T00:00:00Z.
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