15,16-Dihydrotanshinone I inhibits the proliferation of MV4-11 by means of apoptosis via antagonizing FLT3-ITD/STAT5/Mcl-1 pathway

Till now, the medicines approved for acute myeloid leukemia with internal tandem duplication mutation of FMS-like tyrosine kinase 3 (FLT3-ITD) display not ideal efficacy. This study aimed to evaluate the effects of 15,16-dihydrotanshinone I on FLT3-ITD acute myeloid leukemia cells. The inhibitory ef...

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Bibliographic Details
Main Authors: Mansheng Luo (Author), Yanmei Zeng (Author), Xiaoling Deng (Author)
Format: Book
Published: Bangladesh Pharmacological Society, 2023-01-01T00:00:00Z.
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3rd Floor Main Library

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