ArgD of Mycobacterium tuberculosis is a functional N-acetylornithine aminotransferase with moonlighting function as an effective immune modulator

• Main Authors: Iqra Bashir Nehvi (Author), Neha Quadir (Author), Mohd Khubaib (Author), Javaid Ahmad Sheikh (Author), Mohd Shariq (Author), Krishnaveni Mohareer (Author), Sharmistha Banerjee (Author), Syed Asad Rahman (Author), Nasreen Z. Ehtesham (Author), Seyed E. Hasnain (Author)
• Formato: Libro
• Publicado: Elsevier, 2022-01-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

Mycobacterium tuberculosis (M. tuberculosis) encodes an essential enzyme acetyl ornithine aminotransferase ArgD (Rv1655) of arginine biosynthetic pathway which plays crucial role in M. tuberculosis growth and survival. ArgD catalyzes the reversible conversion of N-acetylornithine and 2 oxoglutarate...