Synthesis of New 1, 3, 4-Oxadiazole-Incorporated 1, 2, 3-Triazole Moieties as Potential Anticancer Agents Targeting Thymidylate Synthase and Their Docking Studies

Synthesis of New 1, 3, 4-Oxadiazole-Incorporated 1, 2, 3-Triazole Moieties as Potential Anticancer Agents Targeting Thymidylate Synthase and Their Docking Studies

Thymidylate synthase (TS) has emerged as a hot spot in cancer treatment, as it is directly involved in DNA synthesis. In the present article, nine hybrids containing 1,2,3-triazole and 1,3,4-oxadiazole moieties (<b>6</b>-<b>14</b>) were synthesized and evaluated for anticance...

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Main Authors: Mohammad Mahboob Alam (Author), Abdulraheem SA Almalki (Author), Thikryat Neamatallah (Author), Nada M. Ali (Author), Azizah M. Malebari (Author), Syed Nazreen (Author)
Format: Book
Published: MDPI AG, 2020-11-01T00:00:00Z.
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