New Molecular Mechanisms for Cardiovascular Disease: Contribution of Endothelium-Derived Hyperpolarizing Factor in the Regulation of Vasoconstriction in Peripheral Resistance Arteries

• Main Authors: Xin Jin (Author), Yukiko Satoh-Otonashi (Author), Yoshito Zamami (Author), Shingo Takatori (Author), Narumi Hashikawa-Hobara (Author), Yoshihisa Kitamura (Author), Hiromu Kawasaki (Author)
• Format: Book
• Published: Elsevier, 2011-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract.: Endothelium regulates vascular tone via release of endothelium-derived relaxing factors (EDRF) including nitric oxide (NO), prostaglandin I2 (PGI2), and endothelium-derived hyperpolarizing factor (EDHF). The mesenteric vascular bed produces vascular resistance to develop blood pressure an...