Design, Synthesis and Phenotypic Profiling of Simplified Gedatolisib Analogues

• मुख्य लेखकों: Caroline Marques Xavier Costa (लेखक), Cristiane Aparecida-Silva (लेखक), Luis Eduardo Reina Gamba (लेखक), Thalita Neves de Melo (लेखक), Gisele Barbosa (लेखक), Manoel Oliveira de Moraes Junior (लेखक), Victoria Regina Thomaz de Oliveira (लेखक), Carolinne Souza de Amorim (लेखक), João A. Moraes (लेखक), Eliezer Jesus Barreiro (लेखक), Lídia Moreira Lima (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2023-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Targeted antitumour therapy has revolutionized the treatment of several types of tumours. Among the validated targets, phosphatidylinositol-3 kinase (PI3K) deserves to be highlighted. Several PI3K inhibitors have been developed for the treatment of cancer, including gedatolisib (<b>4</b>...