Design, Synthesis and Phenotypic Profiling of Simplified Gedatolisib Analogues

Design, Synthesis and Phenotypic Profiling of Simplified Gedatolisib Analogues

Targeted antitumour therapy has revolutionized the treatment of several types of tumours. Among the validated targets, phosphatidylinositol-3 kinase (PI3K) deserves to be highlighted. Several PI3K inhibitors have been developed for the treatment of cancer, including gedatolisib (<b>4</b>...

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Main Authors: Caroline Marques Xavier Costa (Author), Cristiane Aparecida-Silva (Author), Luis Eduardo Reina Gamba (Author), Thalita Neves de Melo (Author), Gisele Barbosa (Author), Manoel Oliveira de Moraes Junior (Author), Victoria Regina Thomaz de Oliveira (Author), Carolinne Souza de Amorim (Author), João A. Moraes (Author), Eliezer Jesus Barreiro (Author), Lídia Moreira Lima (Author)
Format: Book
Published: MDPI AG, 2023-01-01T00:00:00Z.
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