Self-Microemulsifying Drug Delivery System to Enhance Oral Bioavailability of Berberine Hydrochloride in Rats

• Main Authors: Xiaolan Chen (Author), Haifeng Yang (Author), Longyu Shi (Author), Yujuan Mao (Author), Lin Niu (Author), Jing Wang (Author), Haifeng Chen (Author), Jiping Jia (Author), Jingxuan Wang (Author), Jiajie Xue (Author), Yan Shen (Author), Chunli Zheng (Author), Yu Tian (Author), Yi Zheng (Author)
• Format: Book
• Published: MDPI AG, 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Berberine hydrochloride (BH) is a versatile bioactive compound derived from the plants of the <i>Berberis</i> genus, known for its various pharmacological effects. However, its oral bioavailability is low due to its high hydrophilicity and limited permeability. To enhance its clinical ef...