Combination of the phosphodiesterase 10A inhibitor, MR1916 with risperidone shows additive antipsychotic‐like effects without affecting cognitive enhancement and cataleptic effects in rats

Abstract Aim Phosphodiesterase 10A (PDE10A) inhibitors not only have antipsychotic‐like effects but also cause cognitive enhancement without affecting extrapyramidal side effects in rodents, suggesting that PDE10A may be a novel approach for the treatment of schizophrenia. However, how a combination...

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Главные авторы: Keita Arakawa (Автор), Shunsuke Maehara (Автор)
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Опубликовано: Wiley, 2020-06-01T00:00:00Z.
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