Subcutaneous implants for long-acting drug therapy in laboratory animals may generate unintended drug reservoirs
Background: Long-acting therapy in laboratory animals offers advantages over the current practice of 2-3 daily drug injections. Yet little is known about the disintegration of biodegradable drug implants in rodents. Objective: Compare bioavailability of buprenorphine with the biodegradation of lipid...
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Main Authors: | Michael Guarnieri (Author), Betty M Tyler (Author), Louis DeTolla (Author), Ming Zhao (Author), Barry Kobrin (Author) |
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Format: | Book |
Published: |
Wolters Kluwer Medknow Publications,
2014-01-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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