Do patient characteristics matter when calculating sample size for eczema clinical trials?

• Main Authors: L. Howells (Author), S. Gran (Author), J. R. Chalmers (Author), B. Stuart (Author), M. Santer (Author), L. Bradshaw (Author), D. M. Gaunt (Author), M. J. Ridd (Author), L. A. A. Gerbens (Author), P. I. Spuls (Author), C. Huang (Author), N. A. Francis (Author), K. S. Thomas (Author)
• Format: Book
• Published: Wiley, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The Patient‐Oriented Eczema Measure (POEM) is the core outcome instrument recommended for measuring patient‐reported atopic eczema symptoms in clinical trials. To ensure that the statistical significance of clinical trial results is meaningful, trials are often designed by specif...