Drug repurposing to tackle parainfluenza 3 based on multi-similarities and network proximity analysis

• Main Authors: Xinyue Chen (Author), Bo Zhou (Author), Xinyi Jiang (Author), Huayu Zhong (Author), Aijing You (Author), Taiyan Zou (Author), Chengcheng Zhou (Author), Xiaoxiao Liu (Author), Yonghong Zhang (Author)
• 格式: 图书
• 出版: Frontiers Media S.A., 2024-10-01T00:00:00Z.
• 主题: article
• 在线阅读: Connect to this object online.

Given that there is currently no clinically approved drug or vaccine for parainfluenza 3 (PIV3), we applied a drug repurposing method based on disease similarity and chemical similarity to screen 2,585 clinically approved chemical drugs using PIV3 potential drugs BCX-2798 and zanamivir as our contro...