Interactions of ABCG2 (BCRP) with epidermal growth factor receptor kinase inhibitors developed for molecular imaging

• Main Authors: Israa eAbdelrahman (Author), Miriam eShmuel (Author), Sara eEyal (Author)
• Formato: Livro
• Publicado em: Frontiers Media S.A., 2014-11-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

The objective of this study was to investigate in vitro the interactions between novel epidermal growth factor receptor kinase inhibitors (EGFRIs) developed for positron emission tomography (PET) imaging and the major efflux transporter breast cancer resistance protein (BCRP/ABCG2). Seven compounds...