Evaluation of two high-throughput proteomic technologies for plasma biomarker discovery in immunotherapy-treated melanoma patients

• Main Authors: Su Yin Lim (Author), Jenny H. Lee (Author), Sarah J. Welsh (Author), Seong Beom Ahn (Author), Edmond Breen (Author), Alamgir Khan (Author), Matteo S. Carlino (Author), Alexander M. Menzies (Author), Richard F. Kefford (Author), Richard A. Scolyer (Author), Georgina V. Long (Author), Helen Rizos (Author)
• Format: Book
• Published: BMC, 2017-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Selective kinase and immune checkpoint inhibitors, and their combinations, have significantly improved the survival of patients with advanced metastatic melanoma. Not all patients will respond to treatment however, and some patients will present with significant toxicities. Hence...