Unannotated single nucleotide polymorphisms in the TATA box of erythropoiesis genes show in vitro positive involvements in cognitive and mental disorders

• Главные авторы: Mikhail Ponomarenko (Автор), Ekaterina Sharypova (Автор), Irina Drachkova (Автор), Irina Chadaeva (Автор), Olga Arkova (Автор), Olga Podkolodnaya (Автор), Petr Ponomarenko (Автор), Nikolay Kolchanov (Автор), Ludmila Savinkova (Автор)
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• Опубликовано: BMC, 2020-10-01T00:00:00Z.
• Предметы: article
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Abstract Background Hemoglobin is a tetramer consisting of two α-chains and two β-chains of globin. Hereditary aberrations in the synthesis of one of the globin chains are at the root of thalassemia, one of the most prevalent monogenic diseases worldwide. In humans, in addition to α- and β-globins,...