Andrade-Oliveira Salvianolic Acid B Modulates Caspase-1-Mediated Pyroptosis in Renal Ischemia-Reperfusion Injury via Nrf2 Pathway

• Main Authors: Yu Pang (Author), Pei-chun Zhang (Author), Rui-rui Lu (Author), Hong-lian Li (Author), Ji-cheng Li (Author), Hong-xin Fu (Author), Yi-Wen Cao (Author), Guo-xing Fang (Author), Bi-hao Liu (Author), Jun-biao Wu (Author), Jiu-yao Zhou (Author), Yuan Zhou (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Acute kidney injury (AKI) is a serious disease characterized by a rapid decline in kidney function. Oxidative stress is the primary pathogenesis of AKI. Salvianolic acid B (SalB), a water-soluble compound extracted from Salvia miltiorrhiza, possesses a potent antioxidant activity. Here, we investiga...