Establishment and Characterization of a Human Small Cell Osteosarcoma Cancer Stem Cell Line: A New Possible In Vitro Model for Discovering Small Cell Osteosarcoma Biology

• Main Authors: Gaia Palmini (Author), Roberto Zonefrati (Author), Cecilia Romagnoli (Author), Alessandra Aldinucci (Author), Carmelo Mavilia (Author), Gigliola Leoncini (Author), Alessandro Franchi (Author), Rodolfo Capanna (Author), Maria Luisa Brandi (Author)
• Format: Book
• Published: Hindawi Limited, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Osteosarcoma (OSA) is the most common primary malignant bone tumor, usually arising in the long bones of children and young adults. There are different subtypes of OSA, among which we find the conventional OS (also called medullary or central osteosarcoma) which has a high grade of malignancy and an...