A Novel Chemically Modified Curcumin Reduces Severity of Experimental Periodontal Disease in Rats: Initial Observations

• Autori principali: Muna S. Elburki (Autore), Carlos Rossa (Autore), Morgana R. Guimaraes (Autore), Mark Goodenough (Autore), Hsi-Ming Lee (Autore), Fabiana A. Curylofo (Autore), Yu Zhang (Autore), Francis Johnson (Autore), Lorne M. Golub (Autore)
• Natura: Libro
• Pubblicazione: Hindawi Limited, 2014-01-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Tetracycline-based matrix metalloproteinase- (MMP-) inhibitors are currently approved for two inflammatory diseases, periodontitis and rosacea. The current study addresses the therapeutic potential of a novel pleiotropic MMP-inhibitor not based on an antibiotic. To induce experimental periodontitis,...