A Novel Chemically Modified Curcumin Reduces Severity of Experimental Periodontal Disease in Rats: Initial Observations

• Main Authors: Muna S. Elburki (Author), Carlos Rossa (Author), Morgana R. Guimaraes (Author), Mark Goodenough (Author), Hsi-Ming Lee (Author), Fabiana A. Curylofo (Author), Yu Zhang (Author), Francis Johnson (Author), Lorne M. Golub (Author)
• Format: Book
• Published: Hindawi Limited, 2014-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Tetracycline-based matrix metalloproteinase- (MMP-) inhibitors are currently approved for two inflammatory diseases, periodontitis and rosacea. The current study addresses the therapeutic potential of a novel pleiotropic MMP-inhibitor not based on an antibiotic. To induce experimental periodontitis,...