m1A inhibition fuels oncolytic virus-elicited antitumor immunity via downregulating MYC/PD-L1 signaling

• Main Authors: Shujin Li (Author), Tian Feng (Author), Yuantong Liu (Author), Qichao Yang (Author), An Song (Author), Shuo Wang (Author), Jun Xie (Author), Junjie Zhang (Author), Bifeng Yuan (Author), Zhijun Sun (Author)
• Format: Book
• Published: Nature Publishing Group, 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract N 1-methyladenosine (m1A) RNA methylation is critical for regulating mRNA translation; however, its role in the development, progression, and immunotherapy response of head and neck squamous cell carcinoma (HNSCC) remains largely unknown. Using Tgfbr1 and Pten conditional knockout (2cKO) mi...