Pharmacological correction of the sequelae of acute alcohol-induced myocardial damage with new derivatives of neuroactive amino acids coupled with the blockade of the neuronal NO synthase isoform

• Main Authors: Margarita V. Kustova (Author), Valentina N. Perfilova (Author), Igor I. Prokofiev (Author), Elena A. Musyko (Author), Aida S. Kucheryavenko (Author), Elena E. Kusnetsova (Author), Diana E. Tsetsera (Author), Ivan N. Tyurenkov (Author)
• Format: Book
• Published: Belgorod National Research University, 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Acute alcohol intoxication (AAI) induces a number of myocardial disorders, which result in mitochondrial dysfunction in cardiomyocytes, oxidative stress, and decreased cardiac contractility. Nitric oxide produced by the nNOS is one of the major modulators of cardiac activity. New deriv...