Analgesia Effect of Enteric Sustained-Release Tetrodotoxin Pellets in the Rat

• Main Authors: Bihong Hong (Author), Jianlin He (Author), Jipeng Sun (Author), Qingqing Le (Author), Kaikai Bai (Author), Yanhua Mou (Author), Yiping Zhang (Author), Weizhu Chen (Author), Wenwen Huang (Author)
• Format: Book
• Published: MDPI AG, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Tetrodotoxin (TTX) was identified as a latent neurotoxin that has a significant analgesia effect. It was rapidly absorbed and excreted in rat after intramuscular (i.m.) injection. To maintain the effect, frequent injections were required. The enteric sustained-release TTX pellets with sucrose pellet...