Procyanidin B2 ameliorates endothelial dysfunction and impaired angiogenesis via the Nrf2/PPARγ/sFlt-1 axis in preeclampsia

• Главные авторы: Lei Liu (Автор), Rencheng Wang (Автор), Ran Xu (Автор), Yuening Chu (Автор), Weirong Gu (Автор)
• Формат: ‌
• Опубликовано: Elsevier, 2022-03-01T00:00:00Z.
• Предметы: article
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Preeclampsia is a severe complication of pregnancy characterised by variable degrees of placental malperfusion. A growing body of evidence indicates that soluble endoglin and soluble fms-like tyrosine kinase-1 (sFlt-1) play important pathophysiological roles in preeclampsia, causing endothelial dysf...