Milnacipran Inhibits Itch-Related Responses in Mice Through the Enhancement of Noradrenergic Transmission in the Spinal Cord

We investigated whether milnacipran, a serotonin-noradrenaline reuptake inhibitor, exhibits an antipruritic effect through the spinal action in mice. Intrathecal injections of milnacipran (0.1 - 10 μg/site) significantly suppressed serotonin-induced biting, which is an itch-related response. However...

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Main Authors: Tsugunobu Andoh (Author), Yoshikazu Gotoh (Author), Yasushi Kuraishi (Author)
Format: Book
Published: Elsevier, 2013-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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