Periodic Heat Stress Licenses EMSC Differentiation into Osteoblasts via YAP Signaling Pathway Activation

• Main Authors: Wentao Shi (Author), Zhe Wang (Author), Lu Bian (Author), Yiqing Wu (Author), Mei HuiYa (Author), Yanjun Zhou (Author), Zhijian Zhang (Author), Qing Wang (Author), Peng Zhao (Author), Xiaojie Lu (Author)
• Format: Book
• Published: Hindawi Limited, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background. The repair and regeneration of large bone defects represent highly challenging tasks in bone tissue engineering. Although recent studies have shown that osteogenesis is stimulated by periodic heat stress, the thermal regulation of osteogenic differentiation in ectomesenchymal stem cells...