Reduced NLRP3 Gene Expression Limits the IL-1β Cleavage via Inflammasome in Monocytes from Severely Injured Trauma Patients

Objective. Traumatic injury or severe surgery leads to a profound immune response with a diminished functionality of monocytes and subsequently their IL-1β release. IL-1β plays an important role in host immunity and protection against infections. Its biological activation via IL-1β-precursor process...

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Bibliographic Details
Main Authors: Shinwan Kany (Author), Johann-Philipp Horstmann (Author), Ramona Sturm (Author), Katharina Mörs (Author), Borna Relja (Author)
Format: Book
Published: Hindawi Limited, 2018-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
Copy 1 Available